Mammalian Target of Rapamycin Is a Therapeutic Target for Murine Ovarian Endometrioid Adenocarcinomas with Dysregulated Wnt/β-Catenin and PTEN

Despite the fact that epithelial ovarian cancers are the leading cause of death from gynecological cancer, very little is known about the pathophysiology of the disease. Mutations in the WNT and PI3K pathways are frequently observed in the human ovarian endometrioid adenocarcinomas (OEAs). However,...

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Main Authors: Tanwar, Pradeep S., Zhang, LiHua, Kaneko-Tarui, Tomoko, Curley, Michael D., Taketo, Makoto M., Rani, Poonam, Roberts, Drucilla J., Teixeira, Jose M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111436/
https://ncbi.nlm.nih.gov/pubmed/21695255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020715
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