Constitutive Activation of Beta-Catenin in Uterine Stroma and Smooth Muscle Leads to the Development of Mesenchymal Tumors in Mice

Leiomyomas and other mesenchymally derived tumors are the most common neoplasms of the female reproductive tract. Presently, very little is known about the etiology and progression of these tumors, which are the primary indication for hysterectomies. Dysregulated WNT signaling through beta-catenin i...

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Autores principales: Tanwar, Pradeep S., Lee, Ho-Joon, Zhang, LiHua, Zukerberg, Lawrence R., Taketo, Makoto M., Rueda, Bo R., Teixeira, Jose M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for the Study of Reproduction, Inc. 2009
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731978/
https://ncbi.nlm.nih.gov/pubmed/19403928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.075648
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