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Stromal deletion of the APC tumor suppressor in mice triggers development of endometrial cancer

The contribution of the stromal microenvironment to the progression of endometrial cancer (EC) has not been well explored. We have conditionally expressed a mutant allele of adenomatous polyposis coli (APC(cKO)) in murine uterine stroma cells to study its effect on uterine development and function....

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Hlavní autoři: Tanwar, Pradeep S., Zhang, LiHua, Roberts, Drucilla J., Teixeira, Jose M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076144/
https://ncbi.nlm.nih.gov/pubmed/21363919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3166
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