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B7-1/2, but not PD-L1/2 molecules, are required on IL-10-treated tolerogenic DC and DC-derived exosomes for in vivo function

Costimulatory molecules such as B7-1/2 and PD-L1/2 play an important role in the function of APC. The regulation of the surface levels of costimulatory molecules is one mechanism by which APC maintain the balance between tolerance and immunity. We examined the contributions of B7-1/2 and PD-L1/2 to...

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Autores principales: Ruffner, Melanie A., Kim, Seon Hee, Bianco, Nicole R., Francisco, Loise M., Sharpe, Arlene H., Robbins, Paul D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075967/
https://ncbi.nlm.nih.gov/pubmed/19757438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939407
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