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The PD-1 Pathway in Tolerance and Autoimmunity
Regulatory T cells (Tregs) and the PD-1: PD-ligand (PD-L) pathway are both critical to terminating immune responses. Elimination of either can result in the breakdown of tolerance and the development of autoimmunity. The PD-1: PD-L pathway can thwart self-reactive T cells and protect against autoimm...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919275/ https://ncbi.nlm.nih.gov/pubmed/20636820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2010.00923.x |
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