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Inhibitors of the PD-1 Pathway in Tumor Therapy

The programmed death 1 (PD-1) pathway delivers inhibitory signals that function as a brake for immune responses. This pathway limits the initiation and duration of immune responses, thereby protecting tissues from immune-mediated damage and autoimmune diseases. However, the PD-1 pathway also inhibit...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: LaFleur, Martin W., Muroyama, Yuki, Drake, Charles G., Sharpe, Arlene H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924692/
https://ncbi.nlm.nih.gov/pubmed/29311378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701044
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