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PD-1 controls Lymph Node and Blood T Follicular Regulatory Cells
Newly defined CD4(+)CXCR5(+)FoxP3(+) T Follicular Regulatory (TFR) cells inhibit CD4(+)CXCR5(+)FoxP3(−) T Follicular Helper (TFH)-mediated humoral immunity. Although PD-1 is expressed by both cell types, the role of this inhibitory receptor on TFR differentiation is unknown. Here we show that PD-1/P...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3788614/ https://ncbi.nlm.nih.gov/pubmed/23242415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2496 |
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