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Dendritic Cell PD-L1 Limits Autoimmunity and Follicular T Cell Differentiation and Function

The PD-1 coinhibitory receptor regulates the balance between T cell activation and tolerance. Although the PD-1 ligands, PD-L1 and PD-L2 are expressed on a variety of cell types, the cell type-specific functions of PD-1 ligands in inducing signals through PD-1 are unknown. Here we use PD-L1 conditio...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Sage, Peter T., Schildberg, Frank A., Sobel, Raymond A., Kuchroo, Vijay K., Freeman, Gordon J., Sharpe, Arlene H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054131/
https://ncbi.nlm.nih.gov/pubmed/29531164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701231
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