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Intestinal Tolerance Is Converted to Autoimmune Enteritis upon PD-1 Ligand Blockade

The B7 family member programmed death-1 ligand (PD-L1) has been shown to play an inhibitory role in the regulation of T cell responses in several organs. However, the role of PD-L1 in regulating tolerance to self-Ags of the small intestine has not been previously addressed. In this study, we investi...

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Main Authors: Reynoso, Erika D., Elpek, Kutlu G., Francisco, Loise, Bronson, Roderick, Bellemare-Pelletier, Angélique, Sharpe, Arlene H., Freeman, Gordon J., Turley, Shannon J.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682217/
https://ncbi.nlm.nih.gov/pubmed/19201863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802769
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