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Exosomes from IDO(+) DC are therapeutic in CIA and DTH disease models
OBJECTIVE: We have demonstrated previously that dendritic cells (DC), modified with immunosuppressive cytokines, and exosomes derived from the DC can suppress the onset of murine CIA and reduce the severity of established arthritis. Indoleamine 2,3-dioxygenase (IDO) is a tryptophan degrading enzyme...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491653/ https://ncbi.nlm.nih.gov/pubmed/19180475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24229 |
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