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B7-1/2, but not PD-L1/2 molecules, are required on IL-10-treated tolerogenic DC and DC-derived exosomes for in vivo function

Costimulatory molecules such as B7-1/2 and PD-L1/2 play an important role in the function of APC. The regulation of the surface levels of costimulatory molecules is one mechanism by which APC maintain the balance between tolerance and immunity. We examined the contributions of B7-1/2 and PD-L1/2 to...

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Autors principals: Ruffner, Melanie A., Kim, Seon Hee, Bianco, Nicole R., Francisco, Loise M., Sharpe, Arlene H., Robbins, Paul D.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075967/
https://ncbi.nlm.nih.gov/pubmed/19757438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939407
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