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Plasma-derived MHCII+ exosomes from tumor-bearing mice suppress tumor antigen-specific immune responses
Tumor-specific immunosuppression is frequently observed in tumor-bearing hosts. Exosomes are nano-sized, endosomal-derived membrane vesicles secreted by most tumor and hematopoietic cells and have been shown to actively participate in immune regulation. We previously demonstrated that antigen-specif...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471134/ https://ncbi.nlm.nih.gov/pubmed/22585706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141978 |
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