The Bryostatin 1 A-Ring Acetate is Not the Critical Determinant for Antagonism of Phorbol Ester-Induced Biological Responses

Samankaltaisia teoksia

• Substitution on the A-Ring Confers to Bryopyran Analogues the Unique Biological Activity Characteristic of Bryostatins and Distinct From That of the Phorbol Esters
  Tekijä: Keck, Gary E., et al.
  Julkaistu: (2009)
• Convergent Assembly of Highly Potent Analogues of Bryostatin 1 via Pyran Annulation: Bryostatin Look-alikes that Mimic Phorbol Ester Function
  Tekijä: Keck, Gary E., et al.
  Julkaistu: (2008)
• Synthesis of seco-B-Ring Bryostatin Analogue WN-1 via C–C Bond-Forming Hydrogenation: Critical Contribution of the B-Ring in Determining Bryostatin-like and Phorbol 12-Myristate 13-Acetate-like Properties
  Tekijä: Andrews, Ian P., et al.
  Julkaistu: (2014)
• Replacement of the Bryostatin A- and B-Pyran Rings With Phenyl Rings Leads to Loss of High Affinity Binding With PKC
  Tekijä: Petersen, Mark E., et al.
  Julkaistu: (2016)
• Synthesis of a des-B-Ring Bryostatin Analogue Leads to an Unexpected Ring Expansion of the Bryolactone Core
  Tekijä: Kraft, Matthew B., et al.
  Julkaistu: (2014)