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Gα(q) Signal in Osteoblasts Is Inhibitory to the Osteoanabolic Action of Parathyroid Hormone

This study examined the role of the Gα(q) signal constituted by Gα(q) and Gα(11) (encoded by Gnα(q) and Gnα(11), respectively), a major intracellular pathway of parathyroid hormone (PTH), in the PTH osteoanabolic action by the gain- and loss-of-function analyses. Transgenic mice with osteoblast-spec...

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Hlavní autoři: Ogata, Naoshi, Shinoda, Yusuke, Wettschureck, Nina, Offermanns, Stefan, Takeda, Shu, Nakamura, Kozo, Segre, Gino V., Chung, Ung-il, Kawaguchi, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075717/
https://ncbi.nlm.nih.gov/pubmed/21345793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200196
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