Krüppel-like Factor 5 Causes Cartilage Degradation through Transactivation of Matrix Metalloproteinase 9

Although degradation of cartilage matrix has been suggested to be a rate-limiting step for endochondral ossification during skeletal development, little is known about the transcriptional regulation. This study investigated the involvement of KLF5 (Krüppel-like factor 5), an Sp/KLF family member, in...

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Detalhes bibliográficos
Main Authors: Shinoda, Yusuke, Ogata, Naoshi, Higashikawa, Akiro, Manabe, Ichiro, Shindo, Takayuki, Yamada, Takashi, Kugimiya, Fumitaka, Ikeda, Toshiyuki, Kawamura, Naohiro, Kawasaki, Yosuke, Tsushima, Kensuke, Takeda, Norifumi, Nagai, Ryozo, Hoshi, Kazuto, Nakamura, Kozo, Chung, Ung-il, Kawaguchi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259811/
https://ncbi.nlm.nih.gov/pubmed/18617520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709857200
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