A new 2'-hydroxyl protecting group for the automated synthesis of oligoribonucleotides.
We have developed a new type of 2'-hydroxyl protecting group for the automated machine synthesis of RNA oligomers: a 2-hydroxyisophthalate formaldehyde acetal (HIFA). The unique feature of this protecting group is that, as the bis ester, it is relatively stable to the acidic conditions that are used...
Sparad:
| I publikationen: | Nucleic Acids Res |
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| Huvudupphov: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Oxford University Press
1995
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| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307477/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8532531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.23.4872 |
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