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Solid phase synthesis of oligoribonucleotides using the o-nitrobenzyl group for 2'-hydroxyl protection and H-phosphonate chemistry.

Oligoribonucleotides with chain length of 7, 11, 15, 17, 24 and 34 were synthesized on long chain alkylamine controlled pore glass beads (LCA-CPG) using o-nitrobenzyl protection of 2'-hydroxyls via a H-phosphonate approach either manually or by using an automatic synthesizer. The oligoribonucle...

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Main Authors: Tanaka, T, Tamatsukuri, S, Ikehara, M
格式: Artigo
語言:Inglês
出版: 1987
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC306245/
https://ncbi.nlm.nih.gov/pubmed/3658693
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