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Solid phase synthesis of oligoribonucleotides using the o-nitrobenzyl group for 2'-hydroxyl protection and H-phosphonate chemistry.

Oligoribonucleotides with chain length of 7, 11, 15, 17, 24 and 34 were synthesized on long chain alkylamine controlled pore glass beads (LCA-CPG) using o-nitrobenzyl protection of 2'-hydroxyls via a H-phosphonate approach either manually or by using an automatic synthesizer. The oligoribonucle...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Tanaka, T, Tamatsukuri, S, Ikehara, M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1987
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306245/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3658693/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.18.7235
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