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Solid phase synthesis of oligoribonucleotides using o-nitrobenzyl protection of 2'-hydroxyl via a phosphite triester approach.

The hepta and undecaribonucleotide were synthesized on a controlled pore glass beads using o-nitrobenzyl protection of 2'-hydroxyls via a phosphite approach. By using 5-p-nitrophenyltetrazole for the activation of nucleoside-phosphoramidite, the condensation reaction was carried out very rapidl...

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Autors principals: Tanaka, T, Tamatsukuri, S, Ikehara, M
Format: Artigo
Idioma:Inglês
Publicat: 1986
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC311635/
https://ncbi.nlm.nih.gov/pubmed/3748809
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