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Synthesis of 2'-modified nucleotides and their incorporation into hammerhead ribozymes.
Several 2'-modified ribonucleoside phosphoramidites have been prepared for structure-activity studies of the hammerhead ribozyme. The aim of these studies was to design and synthesize catalytically active and nuclease-resistant ribozymes. Synthetic schemes for stereoselective synthesis of the R...
Guardado en:
| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1995
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307401/ https://ncbi.nlm.nih.gov/pubmed/7501467 |
| Etiquetas: |
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