Hammerhead ribozymes: importance of stem-loop II for activity.
The activity of several hammerhead ribozyme constructs with constant lengths of stems I and III of 5 nt each but with variously shortened stems II is reported. Stems with 2 bp rather than the conventional 4 bp show essentially unaltered catalytic activity, independent of the composition of the tetra...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1993
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8346207/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.15.6991 |
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