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Hammerhead ribozymes: importance of stem-loop II for activity.

The activity of several hammerhead ribozyme constructs with constant lengths of stems I and III of 5 nt each but with variously shortened stems II is reported. Stems with 2 bp rather than the conventional 4 bp show essentially unaltered catalytic activity, independent of the composition of the tetra...

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Autors principals: Tuschl, T, Eckstein, F
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC47061/
https://ncbi.nlm.nih.gov/pubmed/8346207
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