In vitro selection of hammerhead ribozymes containing a bulged nucleotide in stem II.

Hammerhead ribozymes were transcribed from a dsDNA template containing four random nucleotides between stems II and III, which replace the naturally occurring GAA nucleotides. In vitro selection was used to select hammerhead ribozymes capable of in cis cleavage using denaturing polyacrylamide gels f...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Thomson, J B, Sigurdsson, S T, Zeuch, A, Eckstein, F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146259/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8948630/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.22.4401
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