In vitro selection of hammerhead ribozymes containing a bulged nucleotide in stem II.

Hammerhead ribozymes were transcribed from a dsDNA template containing four random nucleotides between stems II and III, which replace the naturally occurring GAA nucleotides. In vitro selection was used to select hammerhead ribozymes capable of in cis cleavage using denaturing polyacrylamide gels f...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Thomson, J B, Sigurdsson, S T, Zeuch, A, Eckstein, F
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1996
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146259/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8948630/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.22.4401
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