Guanosine 5'-[beta-thio]triphosphate selectively activates calcium signaling in mast cells.
In rat peritoneal mast cells, the activation of GTP-binding proteins (G proteins) by guanosine 5'-[gamma-thio]triphosphate GTP[gamma S] has been found to induce a transient rise in intracellular calcium as well as degranulation. A G protein that couples to phospholipase C (Gp) is thought to mediate...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1992486/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.3.926 |
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