Synthesis of 2'-modified nucleotides and their incorporation into hammerhead ribozymes.
Several 2'-modified ribonucleoside phosphoramidites have been prepared for structure-activity studies of the hammerhead ribozyme. The aim of these studies was to design and synthesize catalytically active and nuclease-resistant ribozymes. Synthetic schemes for stereoselective synthesis of the R isom...
Zapisane w:
| Wydane w: | Nucleic Acids Res |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
1995
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| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307401/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7501467/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.21.4434 |
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