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Aire and T cell Development
In the thymus, developing T cells that react against self-antigens with high affinity are deleted in the process of negative selection. An essential component of this process is the display of self-antigens, including those whose expression are usually restricted to specific tissues, to developing T...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073725/ https://ncbi.nlm.nih.gov/pubmed/21163636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.11.007 |
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