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Pulling RANK on cancer: blocking Aire-mediated central tolerance to enhance immunotherapy

A major breakthrough in cancer treatment occurred with the development of strategies that overcome T-cell tolerance toward tumor cells. These approaches enhance antitumor immunity by overcoming mechanisms that are normally in place to prevent autoimmunity but simultaneously prevent rejection of tumo...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Su, Maureen A., Anderson, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550349/
https://ncbi.nlm.nih.gov/pubmed/31160305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0912
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