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Breaking through the central tolerance ceiling to unleash anticancer immune responses

Central thymic tolerance mechanisms create a formidable barrier against the generation of self-reactive T cells. While preventing autoimmunity, this barrier also limits an effective antitumor immunological response. We recently reported that anti-RANKL blocking antibody breaches this central toleran...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Su, Maureen A, Anderson, Mark S
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292738/
https://ncbi.nlm.nih.gov/pubmed/25610739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.950169
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