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Breaking through the central tolerance ceiling to unleash anticancer immune responses
Central thymic tolerance mechanisms create a formidable barrier against the generation of self-reactive T cells. While preventing autoimmunity, this barrier also limits an effective antitumor immunological response. We recently reported that anti-RANKL blocking antibody breaches this central toleran...
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Publicado no: | Oncoimmunology |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292738/ https://ncbi.nlm.nih.gov/pubmed/25610739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.950169 |
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