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Breaking through the central tolerance ceiling to unleash anticancer immune responses

Central thymic tolerance mechanisms create a formidable barrier against the generation of self-reactive T cells. While preventing autoimmunity, this barrier also limits an effective antitumor immunological response. We recently reported that anti-RANKL blocking antibody breaches this central toleran...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncoimmunology
Egile Nagusiak: Su, Maureen A, Anderson, Mark S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292738/
https://ncbi.nlm.nih.gov/pubmed/25610739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.950169
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