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Enhancement of an anti-tumor immune response by transient blockade of central T cell tolerance
Thymic central tolerance is a critical process that prevents autoimmunity but also presents a challenge to the generation of anti-tumor immune responses. Medullary thymic epithelial cells (mTECs) eliminate self-reactive T cells by displaying a diverse repertoire of tissue-specific antigens (TSAs) th...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010907/ https://ncbi.nlm.nih.gov/pubmed/24752296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131889 |
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