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Canonical microRNAs in thymic epithelial cells promote central tolerance
Medullary thymic epithelial cells (mTECs) facilitate the deletion of developing self-reactive T cells by displaying a diverse repertoire of tissue-specific antigens, a process which largely depends on the expression of the autoimmune regulator (Aire) gene. Mature microRNAs (miRNAs) that regulate gen...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4141217/ https://ncbi.nlm.nih.gov/pubmed/24515814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344079 |
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