Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

The prevention of autoimmunity requires elimination of self-reactive T cells during their development and maturation. Expression of diverse self-antigens by stromal cells in the thymus is essential to this process, and depends, in part, on the activity of the Autoimmune Regulator (Aire) gene. Here w...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Gardner, James M., DeVoss, Jason J., Friedman, Rachel S., Wong, David J., Tan, Ying X., Zhou, Xuyu, Johannes, Kellsey P., Su, Maureen A., Chang, Howard Y., Krummel, Matthew F., Anderson, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532844/
https://ncbi.nlm.nih.gov/pubmed/18687966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1159407
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares