Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire

Homozygous loss-of-function mutations in AIRE cause autoimmune polyglandular syndrome type 1 (APS 1), which manifests in a classic triad of hypoparathyroidism, adrenal insufficiency, and candidiasis. Interestingly, a kindred with a specific G228W AIRE variant presented with an autosomal dominant aut...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Su, Maureen A., Giang, Karen, Žumer, Kristina, Jiang, Huimin, Oven, Irena, Rinn, John L., DeVoss, Jason J., Johannes, Kellsey P.A., Lu, Wen, Gardner, James, Chang, Angela, Bubulya, Paula, Chang, Howard Y., Peterlin, B. Matija, Anderson, Mark S.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2008
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293336/
https://ncbi.nlm.nih.gov/pubmed/18414681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34523
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍