लोड हो रहा है...
Patient mutation in AIRE disrupts P-TEFb binding and target gene transcription
Autoimmune regulator (AIRE) is a transcription factor that induces the expression of a large subset of otherwise strictly tissue restricted antigens in medullary thymic epithelial cells, thereby enabling their presentation to developing T cells for negative selection. Mutations in AIRE lead to autoi...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185428/ https://ncbi.nlm.nih.gov/pubmed/21724609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr527 |
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