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Estrogen turns down “the AIRE”

Genetic alterations are known drivers of autoimmune disease; however, there is a much higher incidence of autoimmunity in women, implicating sex-specific factors in disease development. The autoimmune regulator (AIRE) gene contributes to the maintenance of central tolerance, and complete loss of AIR...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Bakhru, Pearl, Su, Maureen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811114/
https://ncbi.nlm.nih.gov/pubmed/26999606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86800
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