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Estrogen turns down “the AIRE”
Genetic alterations are known drivers of autoimmune disease; however, there is a much higher incidence of autoimmunity in women, implicating sex-specific factors in disease development. The autoimmune regulator (AIRE) gene contributes to the maintenance of central tolerance, and complete loss of AIR...
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Publicado no: | J Clin Invest |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4811114/ https://ncbi.nlm.nih.gov/pubmed/26999606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86800 |
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