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The role of Aire in clonal selection
In his clonal selection theory, Frank Macfarlane Burnet predicted that autoreactive lymphocytes are deleted to prevent autoimmunity. This and other principles of lymphocyte behavior outlined by Burnet guided many studies that lead to our current understanding of thymic selection. Thus, when the gene...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017232/ https://ncbi.nlm.nih.gov/pubmed/21079643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2010.132 |
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