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Aire and T cell Development

In the thymus, developing T cells that react against self-antigens with high affinity are deleted in the process of negative selection. An essential component of this process is the display of self-antigens, including those whose expression are usually restricted to specific tissues, to developing T...

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Detalhes bibliográficos
Main Authors: Anderson, Mark S., Su, Maureen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073725/
https://ncbi.nlm.nih.gov/pubmed/21163636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.11.007
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