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Base Flipping Free Energy Profiles for Damaged and Undamaged DNA
Lesion-induced thermodynamic destabilization is believed to facilitate β-hairpin intrusion by the human XPC/hHR23B nucleotide excision repair (NER) recognition factor, accompanied by partner-base flipping, as suggested by the crystal structure of the yeast orthologue (Min, J. H., and Pavletich, N. P...
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Main Authors: | , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2010
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071897/ https://ncbi.nlm.nih.gov/pubmed/21090780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx1003613 |
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