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Exploring Damage Recognition Models in Prokaryotic Nucleotide Excision Repair with a Benzo[a]pyrene-Derived Lesion in UvrB
The UvrB protein is a central unit for damage recognition in the prokaryotic nucleotide excision repair system, which excises bulky DNA lesions. We have utilized molecular modeling and MD simulations based on crystal structures, mutagenesis, and fluorescence data, to model the 10R-(+)-cis-anti-B[a]P...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2971694/ https://ncbi.nlm.nih.gov/pubmed/19681599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9010072 |
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