Base Flipping Free Energy Profiles for Damaged and Undamaged DNA

Lesion-induced thermodynamic destabilization is believed to facilitate β-hairpin intrusion by the human XPC/hHR23B nucleotide excision repair (NER) recognition factor, accompanied by partner-base flipping, as suggested by the crystal structure of the yeast orthologue (Min, J. H., and Pavletich, N. P...

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Detalhes bibliográficos
Main Authors: Zheng, Han, Cai, Yuqin, Ding, Shuang, Tang, Yijin, Kropachev, Konstantin, Zhou, Yanzi, Wang, Lihua, Wang, Shenglong, Geacintov, Nicholas E., Zhang, Yingkai, Broyde, Suse
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071897/
https://ncbi.nlm.nih.gov/pubmed/21090780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx1003613
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