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Inhibition of Tumor Growth by NK1.1(+) Cells and CD8(+) T Cells Activated by IL-15 through Receptor β/Common γ Signaling in trans

IL-15 is an important cytokine involved in the survival and function of CD8(+) T cells and NK cells. IL-15 can be presented by IL-15Rα (IL-15RA) to bind with the shared IL-2/IL-15Rβ and common γ-chains, which activate signaling pathways on NK cells and CD8(+) T cells. In the present study, we charac...

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書誌詳細
主要な著者: Rowley, Jesse, Monie, Archana, Hung, Chien-Fu, Wu, T.-C.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071607/
https://ncbi.nlm.nih.gov/pubmed/19050240
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