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Inhibition of Tumor Growth by NK1.1(+) Cells and CD8(+) T Cells Activated by IL-15 through Receptor β/Common γ Signaling in trans
IL-15 is an important cytokine involved in the survival and function of CD8(+) T cells and NK cells. IL-15 can be presented by IL-15Rα (IL-15RA) to bind with the shared IL-2/IL-15Rβ and common γ-chains, which activate signaling pathways on NK cells and CD8(+) T cells. In the present study, we charac...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071607/ https://ncbi.nlm.nih.gov/pubmed/19050240 |
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