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IL-15Rα chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation

Natural killer (NK) cells are innate immune effectors that mediate rapid responses to viral antigens. Interleukin (IL)-15 and its high affinity IL-15 receptor, IL-15Rα, support NK cell homeostasis in resting animals via a novel trans presentation mechanism. To better understand how IL-15 and IL-15Rα...

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Detalhes bibliográficos
Main Authors: Mortier, Erwan, Woo, Tammy, Advincula, Rommel, Gozalo, Sara, Ma, Averil
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373851/
https://ncbi.nlm.nih.gov/pubmed/18458113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071913
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