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IL-15.IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cells

Interleukin (IL)-15 and its specific receptor chain, IL-15Rα, support the development of various effector cells, including NK and CD8 T cells via a mechanism called trans-presentation. Whereas the dynamic of trans-presentation has been shown to involve the recycling of IL-15Rα by presenting cells, t...

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Detalhes bibliográficos
Main Authors: Tamzalit, Fella, Barbieux, Isabelle, Plet, Ariane, Heim, Julie, Nedellec, Steven, Morisseau, Sébastien, Jacques, Yannick, Mortier, Erwan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060713/
https://ncbi.nlm.nih.gov/pubmed/24912180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405514111
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