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IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

The in vivo requirements for human natural killer (NK) cell development and differentiation into cytotoxic effectors expressing inhibitory receptors for self–major histocompatability complex class I (MHC-I; killer Ig-like receptors [KIRs]) remain undefined. Here, we dissect the role of interleukin (...

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Bibliographische Detailangaben
Hauptverfasser: Huntington, Nicholas D., Legrand, Nicolas, Alves, Nuno L., Jaron, Barbara, Weijer, Kees, Plet, Ariane, Corcuff, Erwan, Mortier, Erwan, Jacques, Yannick, Spits, Hergen, Di Santo, James P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626663/
https://ncbi.nlm.nih.gov/pubmed/19103877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082013
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