Trans-endocytosis of intact IL-15Rα–IL-15 complex from presenting cells into NK cells favors signaling for proliferation

Interleukin 15 (IL-15) is an essential cytokine for the survival and proliferation of natural killer (NK) cells. IL-15 activates signaling by the β and common γ (γ(c)) chain heterodimer of the IL-2 receptor through trans-presentation by cells expressing IL-15 bound to the α chain of the IL-15 recept...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Anton, Olga M., Peterson, Mary E., Hollander, Michael J., Dorward, David W., Arora, Gunjan, Traba, Javier, Rajagopalan, Sumati, Snapp, Erik L., Garcia, K. Christopher, Waldmann, Thomas A., Long, Eric O.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2020
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955382/
https://ncbi.nlm.nih.gov/pubmed/31871169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911678117
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg