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Expression of IL-15RA or an IL-15/IL-15RA fusion on CD8+ T cells modifies adoptively transferred T cell function in cis

IL-15 and IL-15 receptor alpha (IL-15Rα) play a significant role in multiple aspects of T cell biology. However, given the evidence that IL-15Rα can present IL-15 in trans, the functional capacity of IL-15Rα expressed on CD8+ T cells to modify IL-15 functions in cis is currently unclear. In the curr...

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Detalhes bibliográficos
Main Authors: Rowley, Jesse, Monie, Archana, Hung, Chien-Fu, Wu, T.-C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004157/
https://ncbi.nlm.nih.gov/pubmed/19180469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838594
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