Neprilysin-2 Is an Important β-Amyloid Degrading Enzyme

Proteases that degrade the amyloid-β peptide (Aβ) are important in protecting against Alzheimer's disease (AD), and understanding these proteases is critical to understanding AD pathology. Endopeptidases sensitive to inhibition by thiorphan and phosphoramidon are especially important, because t...

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Главные авторы: Hafez, Daniel, Huang, Jeffrey Y., Huynh, Alexis M., Valtierra, Stephanie, Rockenstein, Edward, Bruno, Angela M., Lu, Bao, DesGroseillers, Luc, Masliah, Eliezer, Marr, Robert A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2011
Предметы:
Regular Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069828/
https://ncbi.nlm.nih.gov/pubmed/21224067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.012
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