Neprilysin-2 Is an Important β-Amyloid Degrading Enzyme

Proteases that degrade the amyloid-β peptide (Aβ) are important in protecting against Alzheimer's disease (AD), and understanding these proteases is critical to understanding AD pathology. Endopeptidases sensitive to inhibition by thiorphan and phosphoramidon are especially important, because t...

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Autores principales: Hafez, Daniel, Huang, Jeffrey Y., Huynh, Alexis M., Valtierra, Stephanie, Rockenstein, Edward, Bruno, Angela M., Lu, Bao, DesGroseillers, Luc, Masliah, Eliezer, Marr, Robert A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2011
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069828/
https://ncbi.nlm.nih.gov/pubmed/21224067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.012
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