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Degradation of Islet Amyloid Polypeptide by Neprilysin

AIMS/HYPOTHESIS: A progressive loss of pancreatic beta-cell function, a decrease in beta-cell mass, and accumulation of islet amyloid is characteristic of type 2 diabetes mellitus. The main constituent of islet amyloid is islet amyloid polypeptide. In this study we have examined the ability of the p...

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Detalhes bibliográficos
Main Authors: Guan, H., Chow, K.M., Shah, R., Rhodes, C.J., Hersh, L.B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660010/
https://ncbi.nlm.nih.gov/pubmed/22898766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2678-y
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